The experimental realization of 2D Bose gases with a tunable interactionstrength is an important challenge for the study of ultracold quantum matter.Here we report on the realization of an optical accordion creating a latticepotential with a spacing that can be dynamically tuned between 11$\,\mu$m and2$\,\mu$m. We show that we can load ultracold $^{87}$Rb atoms into a singlenode of this optical lattice in the large spacing configuration and thendecrease nearly adiabatically the spacing to reach a strong harmonicconfinement with frequencies larger than $\omega_z/2\pi=10\,$kHz. Atoms aretrapped in an additional flat-bottom in-plane potential that is shaped with ahigh resolution. By combining these tools we create custom-shaped uniform 2DBose gases with tunable confinement along the transverse direction and hencewith a tunable interaction strength.
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